Decreased serum levels of mature brain-derived neurotrophic factor

novecsin

Decreased serum ranges of mature brain-derived neurotrophic issue (BDNF), however not its precursor proBDNF, in sufferers with main depressive dysfunction.

BACKGROUND
Meta-analyses have recognized serum ranges of brain-derived neurotrophic issue (BDNF) as a possible biomarker for main depressive dysfunction (MDD).
Nevertheless, on the time, commercially accessible human ELISA kits are unable to differentiate between proBDNF (precursor of BDNF) and mature BDNF due to restricted BDNF antibody specificity. On this research, we examined whether or not serum ranges of proBDNF, mature BDNF, and matrix metalloproteinase-9 (MMP-9), which converts proBDNF to mature BDNF, are altered in sufferers with MDD.
RESULTS
Sixty-nine sufferers with MDD and 78 age- and gender-matched wholesome topics have been enrolled. Sufferers have been evaluated utilizing 17 gadgets on the Structured Interview Information for the Hamilton Despair Score Scale.
Cognitive impairment was evaluated utilizing the CogState battery. Serum ranges of proBDNF, mature BDNF, and MMP-9 have been measured utilizing ELISA kits.
Serum ranges of mature BDNF in sufferers with MDD have been considerably decrease than these of regular controls. In distinction, there was no distinction within the serum ranges of proBDNF and MMP-9 between sufferers and regular controls.
Whereas neither proBDNF nor mature BDNF serum ranges was related to scientific variables, there have been important correlations between MMP-9 serum ranges and the severity of melancholy, high quality of life scores, and social operate scores in sufferers.
CONCLUSIONS
These findings counsel that mature BDNF could function a biomarker for MDD, and that MMP-9 could play a function within the pathophysiology of MDD. Additional research utilizing bigger pattern sizes shall be wanted to examine these outcomes.
novecsin
novecsin

Aimp1 ORF Vector (Mouse) (pORF)

ORF038353 1.0 ug DNA
EUR 607.2

Aimp1 sgRNA CRISPR Lentivector set (Mouse)

K4678901 3 x 1.0 ug
EUR 406.8

AIMP1 siRNA

20-abx907101
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

AIMP1 Peptide

43-036P 0.1 mg
EUR 405.6
Description: AIMP1 Peptide

AIMP1 Peptide

43-037P 0.1 mg
EUR 405.6
Description: AIMP1 Peptide

AIMP1 Peptide

7513P 0.05 mg
EUR 197.7
Description: (CT) AIMP1 Peptide

AIMP1 Protein

20-abx263242
  • EUR 276.00
  • EUR 1930.80
  • EUR 393.60
  • 1 µg
  • 50 ug
  • 5 ug

AIMP1 antibody

70R-12881 100 ul
EUR 548.4
Description: Affinity purified Rabbit polyclonal AIMP1 antibody

AIMP1 Antibody

ABD7261 100 ug
EUR 525.6

AIMP1 Antibody

7513-002mg 0.02 mg
EUR 206.18
Description: AIMP1 (Endothelial monocyte-activating polypeptide II, EMAP2) is a proinflammatory cytokine for monocytes and granulocytes (1). It is specifically induced by apoptosis and is involved in the control of angiogenesis, inflammation, and wound healing (1,2). AIMP1 was identified as one of three auxiliary factors of the mammalian aminoacyl tRNA synthetase (ARS) complex. It binds and facilitates the catalytic reaction of arginyl-tRNA synthetase (2,3). Recent studies show that CD23 plays an essential role in the AIMP1-induced immune response and might be a target in the treatment of inflammatory diseases (4).

AIMP1 Antibody

7513-01mg 0.1 mg
EUR 523.7
Description: AIMP1 (Endothelial monocyte-activating polypeptide II, EMAP2) is a proinflammatory cytokine for monocytes and granulocytes (1). It is specifically induced by apoptosis and is involved in the control of angiogenesis, inflammation, and wound healing (1,2). AIMP1 was identified as one of three auxiliary factors of the mammalian aminoacyl tRNA synthetase (ARS) complex. It binds and facilitates the catalytic reaction of arginyl-tRNA synthetase (2,3). Recent studies show that CD23 plays an essential role in the AIMP1-induced immune response and might be a target in the treatment of inflammatory diseases (4).

AIMP1 Antibody

32755-100ul 100ul
EUR 302.4

AIMP1 Antibody

1-CSB-PA618638DSR1HU
  • EUR 266.40
  • EUR 402.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against AIMP1. Recognizes AIMP1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IP; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000

AIMP1 Antibody

1-CSB-PA618638EA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIMP1. Recognizes AIMP1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200

AIMP1 Antibody

1-CSB-PA584418
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against AIMP1. Recognizes AIMP1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200

AIMP1 Antibody

DF7261 200ul
EUR 420

AIMP1 Antibody

1-CSB-PA181130
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against AIMP1. Recognizes AIMP1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200

AIMP1 Antibody

1-CSB-PA006313
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIMP1. Recognizes AIMP1 from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/10000

AIMP1 Antibody

1-CSB-PA020871GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against AIMP1. Recognizes AIMP1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

AIMP1 Antibody

R34600-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: ARS-interacting multifunctional protein 1

AIMP1 Antibody

R34866-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1, SCYE1

Recombinant Mouse AIMP1 Protein (aa 2-310)

VAng-2917Lsx-100g 100 µg
EUR 1825.2
Description: Recombinant Mouse AIMP1 is expressed in E. coli. (Uniprot ID: P31230)

Recombinant Mouse AIMP1 Protein (aa 2-310)

VAng-2917Lsx-1mg 1 mg
EUR 5751.6
Description: Recombinant Mouse AIMP1 is expressed in E. coli. (Uniprot ID: P31230)

Recombinant Mouse AIMP1 Protein (aa 2-310)

VAng-2917Lsx-500g 500 µg
EUR 3771.6
Description: Recombinant Mouse AIMP1 is expressed in E. coli. (Uniprot ID: P31230)

AIMP1 Protein Vector (Mouse) (pPM-C-HA)

PV153412 500 ng
EUR 723.6

Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

20-abx153613
  • EUR 9004.80
  • EUR 4795.20
  • EUR 1111.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

abx575645-96tests 96 tests
EUR 801.6

Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

DLR-AIMP1-Mu-48T 48T
EUR 679.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

DLR-AIMP1-Mu-96T 96T
EUR 889.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

RDR-AIMP1-Mu-48Tests 48 Tests
EUR 723.6

Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

RDR-AIMP1-Mu-96Tests 96 Tests
EUR 1008

Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

RD-AIMP1-Mu-48Tests 48 Tests
EUR 692.4

Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

RD-AIMP1-Mu-96Tests 96 Tests
EUR 962.4

Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

SEL761Mu-10x96wellstestplate 10x96-wells test plate
EUR 6400.37
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

SEL761Mu-1x48wellstestplate 1x48-wells test plate
EUR 632.27
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

SEL761Mu-1x96wellstestplate 1x96-wells test plate
EUR 851.81
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

SEL761Mu-5x96wellstestplate 5x96-wells test plate
EUR 3473.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

4-SEL761Mu
  • EUR 6460.80
  • EUR 3414.00
  • EUR 852.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) in samples from serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.

AIMP1 Protein Vector (Mouse) (pPB-C-His)

PV153410 500 ng
EUR 723.6

AIMP1 Protein Vector (Mouse) (pPB-N-His)

PV153411 500 ng
EUR 723.6

AIMP1 Protein Vector (Mouse) (pPM-C-His)

PV153413 500 ng
EUR 723.6

Aimp1 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4678902 1.0 ug DNA
EUR 184.8

Aimp1 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4678903 1.0 ug DNA
EUR 184.8

Aimp1 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4678904 1.0 ug DNA
EUR 184.8

Mouse Aimp1( Aminoacyl tRNA synthase complex-interacting multifunctional protein 1) ELISA Kit

EM0741 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 46.9pg/ml

Mouse Aimp1/ Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 ELISA Kit

E0066Mo 1 Kit
EUR 685.2

AIMP1 Rabbit pAb

A5301-100ul 100 ul
EUR 369.6

AIMP1 Rabbit pAb

A5301-200ul 200 ul
EUR 550.8

AIMP1 Rabbit pAb

A5301-20ul 20 ul
EUR 219.6

AIMP1 Rabbit pAb

A5301-50ul 50 ul
EUR 267.6

Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 ELISA Kit (AIMP1)

RK02582 96 Tests
EUR 625.2

Recombinant Mouse AIMP1 Protein (aa 27-158) [His] [T7]

VAng-2923Lsx-100g 100 µg
EUR 1611.6
Description: Recombinant Mouse AIMP1 is expressed in E. coli. (Uniprot ID: Q12904)

Recombinant Mouse AIMP1 Protein (aa 27-158) [His] [T7]

VAng-2923Lsx-1mg 1 mg
EUR 5602.8
Description: Recombinant Mouse AIMP1 is expressed in E. coli. (Uniprot ID: Q12904)

Recombinant Mouse AIMP1 Protein (aa 27-158) [His] [T7]

VAng-2923Lsx-500g 500 µg
EUR 3771.6
Description: Recombinant Mouse AIMP1 is expressed in E. coli. (Uniprot ID: Q12904)

AIMP1 Blocking Peptide

DF7261-BP 1mg
EUR 234

AIMP1 Recombinant Protein

96-820 0.1 mg
EUR 651.3
Description: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1) is also known as multisynthase complex auxiliary component p43 and endothelial monocyte-activating polypeptide II (EMAP-II). AIMP1 is a cytokine that may be induced by apoptosis and is also released from professional antigen-presenting cells such as dendritic cells. The release of AIMP1 renders the tumor-associated vasculature sensitive to tumor necrosis factor. Furthermore, AIMP1 binds tRNA and stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. This protein possesses inflammatory cytokine activity. Also, AIMP1 negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation.

AIMP1 Polyclonal Antibody

A73165
  • EUR 302.50
  • EUR 423.50
  • 50 ul
  • 100 ul

AIMP1 Polyclonal Antibody

A69867
  • EUR 754.26
  • Ask for price
  • Ask for price
  • EUR 470.80
  • 100 ?g
  • 20 ul
  • 50 ul
  • 100 ul

Polyclonal AIMP1 Antibody

APR06854G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human AIMP1 . This antibody is tested and proven to work in the following applications:

AIMP1 Conjugated Antibody

C32755 100ul
EUR 476.4

ELISA kit for Mouse AIMP1 (Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1)

ELK7946 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

AIMP1 protein (His tag)

80R-1611 10 ug
EUR 366
Description: Purified recombinant Human AIMP1 protein

pCDNA3.1-Aimp1-m-6

PVT17584 2 ug
EUR 309.6

Human AIMP1 shRNA Plasmid

20-abx956128
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

AIMP1 Antibody, HRP conjugated

1-CSB-PA618638EB01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIMP1. Recognizes AIMP1 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

AIMP1 Antibody, FITC conjugated

1-CSB-PA618638EC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIMP1. Recognizes AIMP1 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

AIMP1 Antibody, Biotin conjugated

1-CSB-PA618638ED01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIMP1. Recognizes AIMP1 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Recombinant Mouse AIMP1/ EMAP2/ SCYE1 Protein, His-SUMO, E.coli-1mg

QP6654-ec-1mg 1mg
EUR 2763.6

Aimp1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K4678905 3 x 1.0 ug
EUR 451.2

Recombinant Mouse AIMP1/ EMAP2/ SCYE1 Protein, His-SUMO, E.coli-10ug

QP6654-ec-10ug 10ug
EUR 391.2

Recombinant Mouse AIMP1/ EMAP2/ SCYE1 Protein, His-SUMO, E.coli-50ug

QP6654-ec-50ug 50ug
EUR 522

Recombinant Mouse AIMP1/ EMAP2/ SCYE1 Protein, His-SUMO, E.coli-100ug

QP6654-ec-100ug 100ug
EUR 848.4

Recombinant Mouse AIMP1/ EMAP2/ SCYE1 Protein, His-SUMO, E.coli-200ug

QP6654-ec-200ug 200ug
EUR 1338

Recombinant Mouse AIMP1/ EMAP2/ SCYE1 Protein, His-SUMO, E.coli-500ug

QP6654-ec-500ug 500ug
EUR 1816.8

Aimp1 ORF Vector (Rat) (pORF)

ORF063216 1.0 ug DNA
EUR 607.2

AIMP1 ORF Vector (Human) (pORF)

ORF015402 1.0 ug DNA Ask for price

Aimp1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K4678906 1.0 ug DNA
EUR 200.4

Aimp1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K4678907 1.0 ug DNA
EUR 200.4

Aimp1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K4678908 1.0 ug DNA
EUR 200.4

Recombinant Human AIMP1 Protein [His]

VAng-2918Lsx-1mg 1 mg
EUR 5553.6
Description: Recombinant Human AIMP1 is expressed in E. coli. (Uniprot ID: Q12904)

Recombinant Human AIMP1 Protein [His]

VAng-2918Lsx-200g 200 µg
EUR 2848.8
Description: Recombinant Human AIMP1 is expressed in E. coli. (Uniprot ID: Q12904)

Recombinant Human AIMP1 Protein [His]

VAng-2918Lsx-500g 500 µg
EUR 4101.6
Description: Recombinant Human AIMP1 is expressed in E. coli. (Uniprot ID: Q12904)

AIMP1 Polyclonal Antibody, HRP Conjugated

A69868
  • EUR 754.26
  • EUR 293.70
  • EUR 470.80
  • 100 ?g
  • 50 ul
  • 100 ul

AIMP1 Polyclonal Antibody, FITC Conjugated

A69869
  • EUR 754.26
  • EUR 293.70
  • EUR 470.80
  • 100 ?g
  • 50 ul
  • 100 ul

Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

abx251986-96tests 96 tests
EUR 848.4

Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

20-abx150601
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

abx574352-96tests 96 tests
EUR 848.4

Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

DLR-AIMP1-Hu-48T 48T
EUR 664.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

DLR-AIMP1-Hu-96T 96T
EUR 870
Description: A sandwich quantitative ELISA assay kit for detection of Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

RDR-AIMP1-Hu-48Tests 48 Tests
EUR 706.8

Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

RDR-AIMP1-Hu-96Tests 96 Tests
EUR 984

Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1(AIMP1)ELISA Kit

QY-E04344 96T
EUR 433.2

Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

RD-AIMP1-Hu-48Tests 48 Tests
EUR 675.6

Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

RD-AIMP1-Hu-96Tests 96 Tests
EUR 939.6

Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

SEL761Hu-10x96wellstestplate 10x96-wells test plate
EUR 6227.58
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) ELISA Kit

SEL761Hu-1x48wellstestplate 1x48-wells test plate
EUR 618.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Variables that have an effect on assays for plasma cytokines and soluble activation markers.

Cytokines and soluble immune activation markers that replicate cytokine actions in vivo are more and more being measured in plasma, serum, and different physique fluids.
They present helpful diagnostic and prognostic data in addition to perception into illness pathogenesis. Assays of neopterin, beta2-microglobulin, soluble interleukin-2 receptor, and soluble tumor necrosis issue receptor sort II in addition to of the cytokines tumor necrosis issue alpha and gamma interferon (IFN-gamma) have been evaluated by utilizing serum and plasma samples of human immunodeficiency virus (HIV)-positive and HIV-negative topics.
Many components have been discovered to affect the outcomes of those assays. Substantial variations in obvious ranges of analytes have been often discovered when enzyme-linked immunosorbent assay (ELISAkits from totally different producers have been used.
In some circumstances, variations have been discovered within the requirements offered by separate producers. Moreover, the analytic outcomes from totally different a number of ELISA kits provided by single producers differed by as a lot as 50%.
The necessity for uniformity within the requirements for quantitative assays was clearly illustraed. Worldwide reference requirements can be found for cytokines however not for soluble cytokine receptors or soluble activation markers.
Marker ranges in serum or in plasma have been related besides these for IFN-gamma. Many of the analytes have been steady underneath a number of storage circumstances. Thus, batch testing of frozen saved samples is possible.
The findings point out that for longitudinal research, the degrees of cytokines and immune activation markers in plasma or serum ought to be measured by utilizing preverified reagents from one producer.
The high quality of laboratory efficiency can have an effect on scientific relevance. Proficiency testing and exterior high quality assurance applications will help to develop the wanted consensus.
Multi-country analysis of the sensitivity and specificity of two commercially-available NS1 ELISA  assays for dengue prognosis.
BACKGROUND
Early prognosis of dengue can help affected person triage and administration and stop pointless therapies and interventions. Commercially accessible assays that detect the dengue virus protein NS1 within the plasma/serum of sufferers presents the potential for early and speedy prognosis.
RESULTS
The sensitivity and specificity of the Pan-E Dengue Early ELISA and the Platelia Dengue NS1 Ag assays have been in contrast towards a reference prognosis in 1385 sufferers in 6 international locations in Asia and the Americas.
Platelia was extra delicate (66%) than Pan-E (52%) in confirmed dengue circumstances. Sensitivity assorted by geographic area, with each assays typically being extra delicate in sufferers from SE Asia than the Americas.
Each kits have been extra delicate for specimens collected throughout the first few days of sickness onset relative to later time factors. Pan-E and Platelia have been each 100% particular in febrile sufferers with out proof of acute dengue.
In sufferers with different confirmed diagnoses and wholesome blood donors, Platelia was extra particular (100%) than Pan-E (90%). For Platelia, when both the NS1 take a look at or the IgM take a look at on the acute pattern was constructive, the sensitivity versus the reference end result was 82% in samples collected within the first 4 days of fever.
NS1 sensitivity was not related to illness severity (DF or DHF) within the Platelia take a look at, whereas a development for larger sensitivity in DHF circumstances was seen within the Pan-E take a look at (nevertheless mixed with decrease total sensitivity).
CONCLUSIONS
Collectively, this multi-country research means that the perfect performing NS1 assay (Platelia) had reasonable sensitivity (median 64%, vary 34-76%) and excessive specificity (100%) for the prognosis of dengue. The poor sensitivity of the evaluated assays in some geographical areas suggests additional assessments are wanted.
The mixture of NS1 and IgM detection in samples collected within the first few days of fever elevated the total dengue diagnostic sensitivity.

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) ELISA Kit

RDR-SPLUNC3-Hu-48Tests 48 Tests
EUR 706.8

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) ELISA Kit

RDR-SPLUNC3-Hu-96Tests 96 Tests
EUR 984

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) ELISA Kit

SET373Hu-10x96wellstestplate 10x96-wells test plate
EUR 6227.58
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) in Tissue homogenates and other biological fluids.

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) ELISA Kit

SET373Hu-1x48wellstestplate 1x48-wells test plate
EUR 618.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) in Tissue homogenates and other biological fluids.

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) ELISA Kit

SET373Hu-1x96wellstestplate 1x96-wells test plate
EUR 831.48
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) in Tissue homogenates and other biological fluids.

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) ELISA Kit

SET373Hu-5x96wellstestplate 5x96-wells test plate
EUR 3381.66
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) in Tissue homogenates and other biological fluids.

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) ELISA Kit

4-SET373Hu
  • EUR 6288.00
  • EUR 3322.80
  • EUR 831.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

ELISA kit for Human SPLUNC3 (Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3)

ELK6900 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) CLIA Kit

20-abx496268
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) Protein

20-abx655061
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) Antibody

20-abx174542
  • EUR 1111.20
  • EUR 560.40
  • 1 mg
  • 200 ug

Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 3 (SPLUNC3) Antibody

20-abx178388
  • EUR 1579.20
  • EUR 744.00
  • 1 mg
  • 200 ug

Bovine SPLUNC2B ELISA KIT

ELI-52886b 96 Tests
EUR 1113.6

Bovine SPLUNC2A ELISA KIT

ELI-30170b 96 Tests
EUR 1113.6

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) ELISA Kit

20-abx153156
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) ELISA Kit

DLR-SPLUNC2-Hu-48T 48T
EUR 664.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) ELISA Kit

DLR-SPLUNC2-Hu-96T 96T
EUR 870
Description: A sandwich quantitative ELISA assay kit for detection of Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) ELISA Kit

RD-SPLUNC2-Hu-48Tests 48 Tests
EUR 675.6

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) ELISA Kit

RD-SPLUNC2-Hu-96Tests 96 Tests
EUR 939.6

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) ELISA Kit

RDR-SPLUNC2-Hu-48Tests 48 Tests
EUR 706.8

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) ELISA Kit

RDR-SPLUNC2-Hu-96Tests 96 Tests
EUR 984

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) ELISA Kit

SET372Hu-10x96wellstestplate 10x96-wells test plate
EUR 6227.58
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) in serum, plasma, tissue homogenates and other biological fluids.

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) ELISA Kit

SET372Hu-1x48wellstestplate 1x48-wells test plate
EUR 618.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) in serum, plasma, tissue homogenates and other biological fluids.

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) ELISA Kit

SET372Hu-1x96wellstestplate 1x96-wells test plate
EUR 831.48
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) in serum, plasma, tissue homogenates and other biological fluids.

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) ELISA Kit

SET372Hu-5x96wellstestplate 5x96-wells test plate
EUR 3381.66
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) in serum, plasma, tissue homogenates and other biological fluids.

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) ELISA Kit

4-SET372Hu
  • EUR 6288.00
  • EUR 3322.80
  • EUR 831.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) in samples from Serum, plasma, tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

human Splunc2 Antibody

48450-100ul 100ul
EUR 399.6

human Splunc2 Antibody

48450-50ul 50ul
EUR 286.8

human Splunc2 Antibody

abx015999-100ug 100 ug
EUR 493.2

human Splunc2 Antibody

BF0019 200ul
EUR 540

human Splunc2 Blocking Peptide

BF0019-BP 1mg
EUR 234

ELISA kit for Human SPLUNC2 (Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2)

ELK6899 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

human Splunc2 Conjugated Antibody

C48450 100ul
EUR 476.4

Monoclonal human Splunc2 Antibody, Clone: 5B2

APR07899G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human human Splunc2. The antibodies are raised in Mouse and are from clone 5B2. This antibody is applicable in WB, FC, E

Monoclonal human Splunc2 Antibody, Clone: 4C7D7

AMM02920G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human human Splunc2. The antibodies are raised in Mouse and are from clone 4C7D7. This antibody is applicable in WB, FC, E

anti-human Splunc2 (5B2)

LF-MA30704 100 ul
EUR 632.4
Description: Mouse Monoclonal to human Splunc2

SPLUNC1 (22-39)

H-7352.0500 0.5mg
EUR 212.4
Description: Sum Formula: C82H135N21O25; CAS# [1421132-47-9] net

SPLUNC1 (22-39)

H-7352.1000 1.0mg
EUR 332.4
Description: Sum Formula: C82H135N21O25; CAS# [1421132-47-9] net

SPLUNC1 (22-39)

H-7352.5000 5.0mg
EUR 1220.4
Description: Sum Formula: C82H135N21O25; CAS# [1421132-47-9] net

mouse Splunc2 Antibody

BF0461 200ul
EUR 540

mouse Splunc2 Antibody

abx011413-100ug 100 ug
EUR 493.2

anti-mouse Splunc2 (1F12)

LF-MA30712 100 ul
EUR 632.4
Description: Mouse Monoclonal to mouse Splunc2

SPLUNC1 Antibody / BPIFA1

RQ6758 100ug
EUR 356.15
Description: Palate, lung, and nasal epithelium clone protein (PLUNC) is a gene encoding a secretory protein. This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known.

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) CLIA Kit

20-abx496267
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

mouse Splunc2 Blocking Peptide

BF0461-BP 1mg
EUR 234

Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) Protein

20-abx652272
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Monoclonal mouse Splunc2 Antibody, Clone: 1F12

APR07136G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human mouse Splunc2. The antibodies are raised in Mouse and are from clone 1F12. This antibody is applicable in WB and IHC, FC, ICC, E

Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) Antibody

20-abx174541
  • EUR 1111.20
  • EUR 560.40
  • 1 mg
  • 200 ug

Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2) Antibody

20-abx178387
  • EUR 1579.20
  • EUR 744.00
  • 1 mg
  • 200 ug

Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (Splunc2) Antibody

abx011554-100ul 100 ul
EUR 493.2

Recombinant Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2)

4-RPT372Hu01
  • EUR 496.32
  • EUR 256.80
  • EUR 1531.20
  • EUR 590.40
  • EUR 1060.80
  • EUR 408.00
  • EUR 3648.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 expressed in: E.coli

Nori® Equine 6-Plex ELISA Kits-BMP

GR225025 96-well
EUR 629

Nori® Equine 6-Plex ELISA Kits-CCL

GR225026 96-well
EUR 629

Nori® Equine 6-Plex ELISA Kits-MMP

GR225027 96-well
EUR 629

Nori® Equine 6-Plex ELISA Kits-TLR

GR225028 96-well
EUR 629

Nori® Equine 6-Plex ELISA Kits-SAA

GR225030 96-well
EUR 629

Nori® Canine 6-Plex ELISA Kits-BMP

GR226025 96-well
EUR 629

Nori® Canine 6-Plex ELISA Kits-CCL

GR226026 96-well
EUR 629

Nori® Canine 6-Plex ELISA Kits-MMP

GR226027 96-well
EUR 629

Nori® Canine 6-Plex ELISA Kits-TLR

GR226028 96-well
EUR 629

Nori® Canine 6-Plex ELISA Kits-SAA

GR226030 96-well
EUR 629

Nori® Bovine 6-Plex ELISA Kits-BMP

GR228025 96-well
EUR 629

Nori® Bovine 6-Plex ELISA Kits-CCL

GR228026 96-well
EUR 629

Nori® Bovine 6-Plex ELISA Kits-MMP

GR228027 96-well
EUR 629

Nori® Bovine 6-Plex ELISA Kits-TLR

GR228028 96-well
EUR 629

Nori® Bovine 6-Plex ELISA Kits-SAA

GR228030 96-well
EUR 629

Nori® Porcine 6-Plex ELISA Kits-BMP

GR224025 96-well
EUR 629

Nori® Porcine 6-Plex ELISA Kits-CCL

GR224026 96-well
EUR 629

Nori® Porcine 6-Plex ELISA Kits-MMP

GR224027 96-well
EUR 629

Nori® Porcine 6-Plex ELISA Kits-TLR

GR224028 96-well
EUR 629

Nori® Porcine 6-Plex ELISA Kits-SAA

GR224030 96-well
EUR 629

Nori® Equine 6-Plex ELISA Kits-S100

GR225031 96-well
EUR 629

Nori® Equine 6-Plex ELISA Kits-CXCL

GR225032 96-well
EUR 629

Nori® Canine 6-Plex ELISA Kits-S100

GR226031 96-well
EUR 629

Nori® Canine 6-Plex ELISA Kits-CXCL

GR226032 96-well
EUR 629

Nori® Bovine 6-Plex ELISA Kits-S100

GR228031 96-well
EUR 629

Nori® Bovine 6-Plex ELISA Kits-CXCL

GR228032 96-well
EUR 629

Nori® Porcine 6-Plex ELISA Kits-S100

GR224031 96-well
EUR 629

Nori® Porcine 6-Plex ELISA Kits-CXCL

GR224032 96-well
EUR 629

Nori® Equine 6-Plex ELISA Kits-Hormones

GR225029 96-well
EUR 629

Nori® Canine 6-Plex ELISA Kits-Hormones

GR226029 96-well
EUR 629

Nori® Bovine 6-Plex ELISA Kits-Hormones

GR228029 96-well
EUR 629

anti-SPLUNC3

YF-PA22165 50 ug
EUR 435.6
Description: Mouse polyclonal to SPLUNC3

Nori® Porcine 6-Plex ELISA Kits-Hormones

GR224029 96-well
EUR 629

Nori® Equine 3-Plex ELISA Kits-Interferons

GR225009 96-well
EUR 503

Nori® Canine 3-Plex ELISA Kits-Interferons

GR226009 96-well
EUR 503

Nori® Bovine 3-Plex ELISA Kits-Interferons

GR228009 96-well
EUR 503

Nori® Porcine 3-Plex ELISA Kits-Interferons

GR224009 96-well
EUR 503

Human Anti-Chikungunya virus (CHIKV) IgM capture ELISA kits, 96 tests, qualitative

910-705-CHM 1 Kit
EUR 1000.8

Nori® Equine 4-Plex ELISA Kits-Immunoglobulins

GR225017 96-well
EUR 545

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